Transplantation in the Highly Sensitized Pediatric Patient
نویسندگان
چکیده
منابع مشابه
Management of the highly sensitized patient.
One of the major challenges in the current era of organ transplantation is to find suitable organs for highly sensitized patients. Different approaches have been successful in a proportion of the patients. Several organ exchange organizations are currently implementing an acceptable mismatch program similar to the one developed by Eurotransplant. The basis of such a program is the accurate defi...
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The sensitization of patients to human leukocyte antigens prior to heart transplantation is increasingly being recognized as an important challenge both before and after the transplant, and the effects of sensitization on clinical outcomes are just beginning to be understood. Many patients are listed with the requirement of a negative prospective or virtual crossmatch prior to accepting a donor...
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Renal transplantation has had a significant impact on many patients with endstage renal disease. Unfortunately, there exists a large subgroup of dialysis patients who for immunological reasons cannot be transplanted (1). These patients have become sensitized to most or all HLA antigens from previous transplants, blood transfusions, or multiple pregnancies. They react strongly to all kidneys tha...
متن کاملPost-transplantation lymphoproliferative disorder in pediatric patient.
Immunosuppressive therapy for transplanted patients exposes them to a high risk of developing posttransplantation lymphoproliferative disorders (PTLD). We report the case of a child undergoing heart transplantation at seven months of age who developed PTLD at nine years of age, diagnosed by resection of a pulmonary nodule.
متن کاملHeart transplantation in a highly sensitised patient.
Some patients awaiting heart transplantation may develop positive panel reactive antibodies (PRA). Several reports have demonstrated that pre-transplant sensitisation is associated with decreased survival and a higher rejection rate, and leads to the development of cardiac allograft vasculopathy. We describe our experience with a highly sensitised transplant recipient. To reduce sensitisation, ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2014
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.113.001378